Radio Cadena 100 is one of the most popular radio stations in Spain. Its programs are broadcast to the entire Spanish territory, and its generalist programing focuses on adult contemporary music.

Some of the most popular shows are La Noche y Por Ellas, De Sabado with Christian Galvez and Victor Parrado, and La Mejor Variedad Musical. In addition, the station broadcasts generalist programing for audiences of all ages, and organizes concerts for social causes.

The station is owned by the COPE group. The headquarters of Cadena 100 are located in Madrid, Spain. It is the second most popular COPE radio station. Other media include online and mobile.