Material variation definitely affects signals when working with eddy current flaw detectors, but it’s something you learn to manage fairly quickly. Conductivity differences will shift responses, so yes, calibration is important when switching between alloys. However, once reference standards are established, the process becomes routine rather than painful.
Interestingly, we’ve also used eddy current flaw detectors to identify material mix-ups, which turned out to be an unexpected bonus. The method is actually quite versatile in that sense. This explanation helped our team understand how alloy properties influence measurements: https://teqto.pro/flaw-detectors/eddy-current
After some hands-on experience, material differences stop being a problem and start becoming useful information during inspections.