Cannabidiol. - DESENMASCARANDO LAS FALSAS DOCTRINAS

Cannabidiol is a phytocannabinoid, one of at least 113 cannabioids found in the Cannabis sativa plant. The exact antiepileptic mechanism of action of cannabidiol is unknown, however, the drug does not appear to affect the cannabinoid receptors. Unlike tetrahydrocannabinol, it does not cause the development of intoxication and euphoria.
PharmacokineticsTCmax — 2.5-5 hours. The plasma protein binding is over 94 %. The half-life is 56-61 hours.
IndicationsTreatment of convulsions in Lennox-Gastaut syndrome and Dravet syndrome in adults and children from 2 years old.
ContraindicationsHypersensitivity to cannabidiol.
Pregnancy and breastfeedingCategory of action on the fetus according to the FDA — NUse with caution, it is necessary to weigh the risk / benefit ratio for the mother and the fetus/child.
Method of administration and dosageInside.
The initial dose is 2.5 mg / kg 2 times a day. After a week, the dose of cannabidiol can be increased to a maintenance dose of 5 mg/kg 2 times a day (10 mg/kg per day).
If you stop taking cannabidiol, it is recommended to gradually reduce the dose of the drug.
Side effectsDrowsiness, sedation and lethargy, increased liver transaminases, decreased appetite, diarrhea, rash, fatigue, weakness, sleep disorders, infections.