Yes, a prediction platform can support both centralized APIs and decentralized on-chain data — the key is using a hybrid architecture. Most teams pair:

• Centralized data pipelines (CEX price feeds, market APIs, sentiment sources)
  
  

• Decentralized inputs (oracle networks like Chainlink, on-chain metrics, DEX liquidity data)
  
  

The sweet spot is a modular microservices setup where each data source flows into its own ingestion service, then into a unified data normalization + ML processing layer.
This keeps the system scalable, easier to audit, and flexible enough to add or swap new data providers anytime.

Suppose you’re exploring crypto prediction platform development. In that case, hybrid data pipelines are usually the route teams choose today — simply because they give both accuracy and transparency without locking you into one ecosystem.